Metabolic Engineering, Synthetic Biology & Systems Biology
Host organism selection for advantaged commercial product manufacturing with regulatory affairs considerations in mind.
Cellular processes and recombinant metabolic pathway optimizations for host organisms and desired products.
Genetic component library design and automated assembly of gene expression devices.
Precision and untargeted gene and genome engineering (CRISPR, random mutagenesis, etc.).
Recalcitrant (filamentous) microbe engineering, e.g. DNA transformation optimizations, host defense mechanism evasion, undesired DNA removal, and product inhibition mitigation.
Implementation and application of Systems Biology technologies
Fermentation performance analysis using quantitative OMICs data for identification of novel gene targets, rate-limiting enzymatic steps, and undesired products.
Recombinant protein production with optimized manufacturing host organisms and expression technologies.
Technical Development Plan creation.
Technology Due Diligence
Technology portfolio and associated risk assessment to determine success or failure of financial investments in M&A.
IP/FTO Analysis & Patent Strategy
In-force patent and published patent application identification for risk assessment of potential claim infringement covering targeted products, processes, and technologies.
Freedom-To-Operate analysis for detection of barriers to product and technology commercialization.
Comprehensive patent strategy development to create strong, business-savvy IP portfolio.
New patent application generation and patentability searches.
Invention Disclosure and Trade Secret process development.
Regulatory Affairs
Regulatory strategy design in the initial product development phase for accelerated revenue generation.
Biotechnology submission filings under EPA's TSCA requirements for commercialization of bioproducts from intergeneric microorganism.